Warren Hochfeld It was a most peculiar newspaper headline, on 8 December 2003 the British broadsheet newspaper the Independent announced: ‘Glaxo chief: ‘ Our drugs do not work on most patients’. The subsequent report covered a conference at which Allen Roses, vice-president of genetics at the pharmaceutical giant GlaxoSmithKline, admitted the ‘open secret within the drugs industry’, that fewer than half of the patients prescribed some of the most expensive drugs actually derived any benefit from them. This could be a quick way to a self-induced sacking, except that this isn't the revelation...